Amey, Ronald L.; Martin, J. C. published the artcile< Synthesis and reactions of stable alkoxyaryltrifluoroperiodinanes. A ""tamed"" analog of iodine pentafluoride for use in oxidations of amines, alcohols, and other species>, Synthetic Route of 112-63-0, the main research area is iodinane per alkoxyaryl trifluoro; periodinane alkoxyaryl trifluoro; oxidation periodinane alc amine; iodine pentafluoride analog; benziodoxole preparation reaction.
Stable alkoxyaryltrifluoroperiodinanes I and II were prepared by oxidation of the resp. parent iodo alcs. 5,2-MeIC6H3C(CF3)2OH and 2-IC6H4CMe2OH with excess CF3OF. The stability and low reactivity of I and II are ascribed to the strong stabilizing influence of the 5-membered ring. The reaction of I with Me3SiCl gives the corresponding iodine(III) species, III, and chlorine. I is hydrolyzed with aqueous base to give a species thought to be iodinane oxide (IV). I is a selective reagent for the oxidation of primary and secondary amines or alcs. bearing α hydrogens to the corresponding aldehyde or ketone. In contrast to iodine pentafluoride, I does not further oxidize the product aldehydes to acids. tert-Butylamine is oxidized by I to give 1,1,1′,1′-tetramethylazoethane. PhMgBr reacts with I to give PhF. Possible mechanisms for these selective oxidations are discussed. It is suggested that the stabilizing structural features of I make it a tamed analog of IF5.
Journal of the American Chemical Society published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics