Specklin, Simon; Cossy, Janine published the artcile< Chemoselective Synthesis of β-Ketophosphonates Using Lithiated α-(Trimethylsilyl)methylphosphonate>, Synthetic Route of 71195-85-2, the main research area is lithiated methylsilylmethyl phosphonate preparation coupling pentafluorophenyl ester; ketophosphonate preparation.
A highly chemoselective synthesis of β-ketophosphonates from pentafluorophenyl esters and lithiated Me α-(trimethylsilyl)methylphosphonate was developed. This mild lithiated phosphonate reagent gave functionalized β-ketophosphonates, e.g., PhC(O)CH2P(O)(OMe)2, in the presence of unactivated esters with high yields. This method was compared with the standard lithiated methylphosphonate reagent.
Journal of Organic Chemistry published new progress about Esters Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (pentafluorophenyl esters). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Synthetic Route of 71195-85-2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics