Li, Bao Qiong; Li, Xin Kang; Lin, Yuan; Li, Ze Ying; Zhang, Xiang-Zhi; Feng, Na; Ma, Ai-Jun; Chen, Chao Yang; Tan, Lin Fan published the artcile< Development and validation of ultra-high performance supercritical fluid chromatography method for quantitative determination of six compounds in Guizhi Fuling capsule and tablet samples>, SDS of cas: 112-63-0, the main research area is Guizhi fuling formula; multiple compounds; ultra-high performance supercritical fluid chromatography.
A fast and simple ultra-high performance supercritical fluid chromatog. method has been developed for the determination of six analytes, namely (paeonol, coumarin, cinnamic alc., cinnamic acid, paeoniflorin, and amygdalin) in Guizhi Fuling capsule and tablet samples. The influence of the key chromatog. parameters for the separation purposes was evaluated. The optimal column was Trefoil CEL1 column. The optimal mobile phase was a gradient mixture of carbon dioxide and methanol at flow rate of 1.0 mL/min. The back pressure of the system was set to 1.38 x 107 Pa and the temperature to 45°C. The six compounds were separated within 11 min by the proposed ultra-high performance supercritical fluid chromatog. method with satisfactory resolution Method validation confirmed that the procedure is accurate with the recovery rates from 87.04 to 104.30%, intraday precision values less than 4.81% and interday precision less than 5.22%, and linear with R2 higher than 0.9967. Therefore, this work provides a simple and novel method for the simultaneous anal. of six compounds in Guizhi Fuling capsule and tablet samples.
Journal of Separation Science published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics