Nykaza, Trevor V.; Li, Gen; Yang, Junyu; Luzung, Michael R.; Radosevich, Alexander T. published the artcile< PIII/PV=O Catalyzed Cascade Synthesis of N-Functionalized Azaheterocycles>, Application In Synthesis of 30095-98-8, the main research area is azaheterocycle preparation organophosphorus catalyst cascade; cross-coupling; cyclization; nitrogen heterocycles; organocatalysis; phosphorus.
An organocatalytic method for the modular synthesis of diverse N-aryl and N-alkyl azaheterocycles (indoles, oxindoles, benzimidazoles, and quinoxalinediones) is reported. The method employs a small-ring organophosphorus-based catalyst (1,2,2,3,4,4-hexamethylphosphetane P-oxide) and a hydrosilane reductant to drive the conversion of ortho-functionalized nitroarenes into azaheterocycles through sequential intermol. reductive C-N cross coupling with boronic acids, followed by intramol. cyclization. This method enables the rapid construction of azaheterocycles from readily available building blocks, including a regiospecific approach to N-substituted benzimidazoles and quinoxalinediones.
Angewandte Chemie, International Edition published new progress about Aromatic nitro compounds Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (o-acylamino). 30095-98-8 belongs to class esters-buliding-blocks, and the molecular formula is C9H9NO4, Application In Synthesis of 30095-98-8.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics