Mabit, Thibaud; Siard, Aymeric; Legros, Frederic; Guillarme, Stephane; Martel, Arnaud; Lebreton, Jacques; Carreaux, Francois; Dujardin, Gilles; Collet, Sylvain published the artcile< Stereospecific C-Glycosylation by Mizoroki-Heck Reaction: A Powerful and Easy-to-Set-Up Synthetic Tool to Access α- and β-Aryl-C-Glycosides>, Quality Control of 4098-06-0, the main research area is transition state palladium glycal crystal structure; cross coupling aryl C glycoside synthesis glycosylation Mizoroki Heck; C-glycosides; Mizoroki-Heck reaction; cross-coupling; α-glycosylation; β-glycosylation.
A stereospecific Mizoroki-Heck cross-coupling of differently substituted glycals with haloarenes resulting in the exclusive formation of either α- or β-aryl-C-glycosides depending solely on the configuration at C3 was achieved. The reaction was easy to set up because no specific precautions were required concerning moisture or oxygen, and it proceeded by a chirality transfer from C3 to C1. After optimization of cross-coupling conditions, various prepared glycals (7 examples) and arenes (10 examples) were tested, leading stereospecifically to the corresponding aryl-C-glycosides with a carbonyl group at C3, thus opening up new horizons for the total synthesis of glycosylated natural products.
Chemistry – A European Journal published new progress about C-Glycosides, aryl Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 4098-06-0 belongs to class esters-buliding-blocks, and the molecular formula is C12H16O7, Quality Control of 4098-06-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics