Luo, Ziwei; Tsui, Gavin Chit published the artcile< Radical cyclization/bis(pentafluoroethylation) of 1,6-dienes using HCF2CF3-derived CuCF2CF3>, Application of C11H19NO2, the main research area is pyrrolidine pentafluoropropyl preparation diastereoselective; diallylamine copper pentafluoroethyl radical cyclization pentafluoroethylation; pentafluoropropyl cyclopentane preparation diastereoselective; diallyl malonate copper pentafluoroethyl radical cyclization pentafluoroethylation.
A domino radical cyclization/bis(pentafluoroethylation) of 1,6-dienes CH2=CHCH2N(R)CH2C(=CH2)R1 (R = H, 4-H3CC6H4SO2, 2,6-bis(propan-2-yl)phenyl, CH2CH=CH2, etc.; R1 = H, Me), and CH2=CHCH2C(R2)(R3)CH2CH=CH2 [R2 = R3 = C(O)OEt, C(O)OPh, C(O)Bn, etc. R2R3 = -C(O)(CH2)3C(O)-] for the synthesis of new classes of pyrrolidine I and cyclopentane derivatives II containing two C2F5 groups was described. This reaction is efficient for constructing three carbon-carbon bonds in one step. The reagent [CuCF2CF3] is prepared from inexpensive pentafluoroethane and the reactions conveniently run at room temperature in open air. Moderate to good diastereoselectivities can be obtained favoring the cis products I with X-ray structural proof.
Organic Chemistry Frontiers published new progress about Alkadienes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 151259-38-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H19NO2, Application of C11H19NO2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics