Hussain, Nazar; Babu Tatina, Madhu; Mukherjee, Debaraj published the artcile< Cross dehydrogenative coupling of sugar enol ethers with terminal alkenes in the synthesis of pseudo-disaccharides, chiral oxadecalins and a conjugated triene>, Synthetic Route of 4098-06-0, the main research area is Diels Alder cycloaddition oxadecalin stereoselective dehydrogenative coupling disaccharide; maleic anhydride cycloaddition oxadecalin stereoselective dehydrogenative coupling disaccharide preparation; oxadecalin disaccharide dehydrogenative stereoselective coupling alkene triene.
An efficient strategy for the synthesis of C-2 and C-3 branched sugar dienes via cross dehydrogenative coupling of sugar enol ethers with terminal alkenes was developed. Both pyran and furan based enol ethers coupled smoothly with electron rich as well as deficient alkene sources yielding sugar dienes with complete E-stereoselectivity. This coupling reaction was applied successfully for the synthesis of orthogonally protected pseudo-C-saccharides as an alternative to olefin metathesis. Substrate scope was further enhanced by reacting exo-glycals with Me acrylate to generate C-5 branched sugars with moderate diastereoselectivity. These diene subunits were reacted with maleic anhydride under [4+2] cycloaddition conditions to generate highly functionalized chiral oxadecalin cores. Finally, utilizing this C-C bond formation, a sugar based conjugated triene was synthesized in excellent yield and selectivity.
Organic & Biomolecular Chemistry published new progress about Coupling reaction. 4098-06-0 belongs to class esters-buliding-blocks, and the molecular formula is C12H16O7, Synthetic Route of 4098-06-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics