De Angelis, Martina; Primitivo, Ludovica; Lucarini, Claudia; Agostinelli, Sonia; Sappino, Carla; Ricelli, Alessandra; Righi, Giuliana published the artcile< Stereocontrolled total synthesis of iminosugar 1,4-dideoxy-1,4-imino-D-iditol>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is alditol iminosugar potential antiviral antitumor antidiabetic antituberculosis antibacterial alkaloid; iminosugar deoxyiminoiditol alditol preparation stereoselective hydroxylation deoxyiminogalactitol; 1,4-Dideoxy-1,4-imino-D-galactitol; 1,4-Dideoxy-1,4-imino-D-iditol; Asymmetric dihydroxylation; Iminosugars.
The first stereocontrolled total synthesis of iminosugar 1,4-dideoxy-1,4-imino-D-iditol is described. The key step in our approach was the double diastereo-selection in the asym. dihydroxylation (AD) of suitable optically active olefin, the chiral vinyl azido alc. Performing the AD using the most common Cinchona alkaloids as ligands enabled us to identify the ligand of choice for the stereodivergent synthesis of 1,4-dideoxy-1,4-imino-D-iditol and 1,4-dideoxy-1,4-imino-D-galactitol. These type of iminosugars, both natural and unnatural, are intensively studied for their promising chemotherapeutic properties against viral infections, diabetes, cancer, and tuberculosis.
Carbohydrate Research published new progress about Alditols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics