Soda, Anil Kumar team published research in ChemistrySelect in 2022 | 87-13-8

87-13-8, Diethyl ethoxymethylenemalonate is a useful research compound. Its molecular formula is C10H16O5 and its molecular weight is 216.23 g/mol. The purity is usually 95%.

Diethyl ethoxymethylidenemalonate is a matrix effect reagent used in analytical chemistry. It is often used as a substrate for the cycloaddition process, which produces malondialdehyde and hydrochloric acid. The UV-absorption of the malondialdehyde can be measured to determine the concentration of the sample. Diethyl ethoxymethylidenemalonate is also used as a dna template in binding constants, where it binds with amines to form complexes that are then analyzed by light emission. It has been shown to have an inhibitory effect on gyrase and trifluoroacetic acid, both enzymes involved in DNA replication., SDS of cas: 87-13-8

Polyesters are important plastics, with monomers linked by ester moieties. Phosphoesters form the backbone of DNA molecules. 87-13-8, formula is C10H16O5, Name is Diethyl 2-(ethoxymethylene)malonate.Nitrate esters, such as nitroglycerin, are known for their explosive properties. SDS of cas: 87-13-8.

Soda, Anil Kumar;Kurva, Srinivas;Singh, Kamini;Veeragoni, Dileepkumar;Misra, Sunil;Murahari, Manikanta;Madabhushi, Sridhar research published 《 Synthesis and Pharmacological Evaluation of Hexafluoro Functionalized Quinolone Derivatives as Potential Chemotherapeutic Agents》, the research content is summarized as follows. Synthesizedma series of compound I [R1= R2 = R3 = H, Et; X = H, 8-F, 5-Cl, 8-Cl] from aryl amines as novel chemotherapeutic agents. The compound I [ R1 = Et; R2 = R3= OH; X= 5-Cl] exhibited the most potent promising antimicrobial and antibiofilm activity against Gram-pos. Staphylococcus aureus MTCC96 with a min. bactericidal concentration (MBC) value of 1.8 μg/mL and an IC50 value of 15.6 ± 0.04 μM. The presence of ester linkage, electron withdrawing chlorine ortho (5-Cl) to hexafluoro-2-propanol and an unsubstituted nitrogen in the quinolone scaffold enhanced the antimicrobial activity. The compounds I [R1= R2 = R3 = H, Et; X = H, 8-F, 5-Cl] was displayed a significant cytotoxicity towards cancer cells without any toxic effects towards the normal cells.

87-13-8, Diethyl ethoxymethylenemalonate is a useful research compound. Its molecular formula is C10H16O5 and its molecular weight is 216.23 g/mol. The purity is usually 95%.

Diethyl ethoxymethylidenemalonate is a matrix effect reagent used in analytical chemistry. It is often used as a substrate for the cycloaddition process, which produces malondialdehyde and hydrochloric acid. The UV-absorption of the malondialdehyde can be measured to determine the concentration of the sample. Diethyl ethoxymethylidenemalonate is also used as a dna template in binding constants, where it binds with amines to form complexes that are then analyzed by light emission. It has been shown to have an inhibitory effect on gyrase and trifluoroacetic acid, both enzymes involved in DNA replication., SDS of cas: 87-13-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics