Salvatore, Ralph N.; Chu, Feixia; Nagle, Advait S.; Kapxhiu, Elona A.; Cross, Richard M.; Jung, Kyung Woon published the artcile< Efficient Cs2CO3-promoted solution and solid phase synthesis of carbonates and carbamates in the presence of TBAI>, Product Details of C6H10O5, the main research area is carbamate carbonate preparation cesium carbonate tetrabutylammonium iodide; solid phase preparation carbamate carbonate; carbon dioxide reaction alc amine alkyl halide.
Novel solution and solid-phase methods for the synthesis of carbonates and carbamates were developed using cesium bases and TBAI via a three-component coupling. Cesium carbonate not only promoted successful carbonylations of alcs. and carbamations of amines, but also suppressed common side reactions traditionally seen using existing protocols. Various alcs. and amines were examined, using a wide array of alkyl halides, and the results demonstrated that this methodol. was highly chemoselective. In particular, use of either sterically demanding substrates or amino acid derivatives afforded the corresponding products exclusively, offering a wide variety of applications such as novel protecting groups and peptidomimetic syntheses.
Tetrahedron published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Product Details of C6H10O5.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics