Feng, Sitian’s team published research in Organic Letters in 2020-10-02 | 94-02-0

Organic Letters published new progress about Enantioselective synthesis. 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Related Products of 94-02-0.

Feng, Sitian; Tang, Yitian; Yang, Chenjue; Shen, Chaoren; Dong, Kaiwu published the artcile< Synthesis of Enantioenriched 浼?浼?Difluoro-灏?arylbutanoic Esters by Pd-Catalyzed Asymmetric Hydrogenation>, Related Products of 94-02-0, the main research area is aryldifluorobutanoate enantioselective preparation; palladium catalyst enantioselective hydrogenation aryldifluorobutenoate.

Synthesis of optically active gem-difluorinated organic mols. attracts a great deal of interest due to their unique properties in pharmaceutical and agrochem. areas. Herein, a series of enantioenriched 浼?浼?difluoro-灏?arylbutanoic esters such as (S)-(-)-4-PhC6H4CHMeCF2CO2Et were prepared in high yields (83-99%) with moderate to excellent enantioselectivities (閳?7:3 er) by palladium-catalyzed asym. hydrogenation.

Organic Letters published new progress about Enantioselective synthesis. 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Related Products of 94-02-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics