On May 4, 1984, Makosza, Mieczyslaw; Winiarski, Jerzy published an article.Quality Control of tert-Butyl 2-(4-nitrophenyl)acetate The title of the article was Reactions of organic anions. Part 110. Vicarious nucleophilic substitution of hydrogen in nitroarenes with α-substituted nitriles and esters. Direct α-cyanoalkylation and α-carbalkoxyalkylation of nitroarenes. And the article contained the following:
Carbanions generated from alkanenitriles bearing α-chloro, α-OR (R = Me, Ph, chlorophenyl) or α-SR (R = Me, Ph, Me2NCS) groups and from aliphatic esters bearing α-SR groups react with mononitroarenes to replace H atoms of the nitroarom. ring ortho or para to the NO2 group with α-cyanoalkyl or α-carbalkoxyalkyl substituents. The nucleophilic replacement of H with such carbanions proceeds faster than substitution of halogen ortho or para to the NO2 group. The experimental process involved the reaction of tert-Butyl 2-(4-nitrophenyl)acetate(cas: 29704-38-9).Quality Control of tert-Butyl 2-(4-nitrophenyl)acetate
The Article related to vicarious nucleophilic substitution nitroarene, cyanoalkylation nitroarene, carbalkoxyalkylation nitroarene, nitroarene cyanoalkylation carbalkoxyalkylation, alkylation cyano carbalkoxy nitroarene, alkanenitrile chloro oxy thio anion, chloroalkanenitrile anion reaction, oxyalkanenitrile anion reaction, thioalkanenitrile anion reaction and other aspects.Quality Control of tert-Butyl 2-(4-nitrophenyl)acetate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics