Chan, Chieh-Kai; Lai, Chien-Yu; Wang, Cheng-Chung published the artcile< Environmentally Friendly Nafion-Mediated Friedlander Quinoline Synthesis under Microwave Irradiation: Application to One-Pot Synthesis of Substituted Quinolinyl Chalcones>, Formula: C11H12O3, the main research area is quinoline preparation green chem microwave irradiation; aminobenzophenone carbonyl synthon Friedlander reaction Nafion catalyst; quinolinyl chalcone preparation green chem microwave irradiation diastereoselective; benzaldehyde aminobenzophenone carbonyl synthon Friedlander reaction Nafion catalyst.
An efficient and eco-friendly synthetic route for Friedlander quinoline synthesis of polysubstituted quinolines e.g., I is described. This green chem. method starts from various 2-aminobenzophenones 2-NH2-5-R-6-R1-C6H2C(O)(R2) (R = H, Cl, Me, Ph, etc.; R1 = H; RR1 = -CH=CH-CH=CH-; R2 = H, Me, Ph, 2-chlorophenyl, etc.) and mono- or dicarbonyl synthons such as acetylacetone, cyclohexanone, 1,2-diphenylethan-1-one, etc. and uses reusable Nafion NR 50 material as a solid catalyst in ethanol under microwave irradiation The protocol has a high generality of functional groups and provides the desired quinolines e.g., I in good to excellent yields. Some structures were confirmed by single-crystal X-ray diffraction anal.
Synthesis published new progress about Aromatic amines Role: RCT (Reactant), RACT (Reactant or Reagent). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Formula: C11H12O3.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics