《Nano cuboids: Impact of 8-hydroxyquinoline on tryptophan properties and its applications》 was written by Singh, Prabhpreet; Sharma, Poonam. Application In Synthesis of H-Trp-OMe.HCl And the article was included in Tetrahedron Letters in 2020. The article conveys some information:
N-terminal tryptophan residues can be labeled with fluorophore by chem. reaction. Here in we report conjugation of 8-hydroxyquinoline (as fluorophore) with tryptophan using Schiff-base condensation reaction to decipher the impact of 8-hydroxyquinoline on the fluorescence and self-assembly properties of tryptophan in water. This water-soluble hydroxyquinoline-tryptophan (HQ-W1) conjugate has been demonstrated to have Aggregation Induced Emission (AIE) phenomena in water. HQ-W1 undergo spontaneous self-assembly to form nano cuboidal superstructures having 200-500 nm diameter and 300-650 nm length. In metal-ion binding studies this HQ-W1 shows selective fluorescence enhancement (14.5-fold) in the presence of Al3+ ions. The detection limit is 3.0 nM (UV method) and 3.53 nM (FI method). The AIE utility of HQ-W1 has been demonstrated by developing latent fingerprints. In the experiment, the researchers used many compounds, for example, H-Trp-OMe.HCl(cas: 7524-52-9Application In Synthesis of H-Trp-OMe.HCl)
H-Trp-OMe.HCl(cas:7524-52-9) is one of amino acid derivatives. Amino acid derivatives represent an important category of skin penetration promoters. These compounds possess hydrophobic chains attached to an amino acid headgroup via a biodegradable ester bond. Due to the amphiphilic nature of these derivatives, it is possible for them to enter into the SC lipid barrier and significantly disorganize skin membrane lipids.Application In Synthesis of H-Trp-OMe.HCl
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