In 2022,Li, Zhao-Feng; He, Hong-Jiao; Wang, Rong-Hui; Zhou, Li-Yan; Xiao, You-Cai; Chen, Fen-Er published an article in Organic Chemistry Frontiers. The title of the article was 《Copper-catalyzed asymmetric alkynylation of pyrazole-4,5-diones using chloramphenicol base-derived hydroxyl oxazoline ligands》.Application of 4949-44-4 The author mentioned the following in the article:
The asym. copper-catalyzed alkynylation reactions of pyrazole 4,5-diones in the presence of a hydroxyl oxazoline ligand, which was derived from low cost, easily accessible chloramphenicol base (ANP), was reported. The notable features of this protocol include its mild and base additive free reaction conditions and broad functional group tolerance. In addition to this study using Ethyl 3-oxopentanoate, there are many other studies that have used Ethyl 3-oxopentanoate(cas: 4949-44-4Application of 4949-44-4) was used in this study.
Ethyl 3-oxopentanoate(cas: 4949-44-4) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Application of 4949-44-4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics