《Tetra-substituted furans by a gold-catalysed tandem C(sp3)-H alkynylation/oxy-alkynylation reaction》 was published in Organic Chemistry Frontiers in 2021. These research results belong to Han, Chunyu; Tian, Xianhai; Song, Lina; Liu, Yaowen; Hashmi, A. Stephen K.. Category: esters-buliding-blocks The article mentions the following:
A gold-catalyzed cascade C(sp3)-H alkynylation/oxy-alkynylation of acceptor-substituted carbonyl compounds with hypervalent iodine(III) reagents for the synthesis of tetra-substituted furans is described. This reaction involves two Au(I)/Au(III) catalytic cycles and proceeds through a C(sp3)-H alkynylation of a substituted ketone and a subsequent oxy-alkynylation of the generated 2-alkynyl ketone. This mild and simple method can tolerate a wide range of functionalities, offering distinct advantages over previous methods using PIDA as the external oxidant. Furthermore, a gram-scale synthesis is feasible and the synthesized furan product was readily transformed into other related compounds The results came from multiple reactions, including the reaction of Methyl 3-oxovalerate(cas: 30414-53-0Category: esters-buliding-blocks)
Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. Ketone compounds have important physiological properties. They are found in several sugars and in compounds for medicinal use, including natural and synthetic steroid hormones. Molecules of the anti-inflammatory agent cortisone contain three ketone groups.Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics