Gan, Ziyu; Li, Guoqing; Yan, Qiuli; Deng, Weiseng; Jiang, Yuan-Ye; Yang, Daoshan published the artcile< Visible-light-promoted oxidative desulphurisation: a strategy for the preparation of unsymmetrical ureas from isothiocyanates and amines using molecular oxygen>, Computed Properties of 19241-24-8, the main research area is unsym urea preparation photochem green chem; isothiocyanate amine oxidative desulfurization photoredox catalyst.
A green and efficient visible-light promoted oxidative desulfurization protocol has been proposed for the construction of unsym. ureas R1NHC(O)N(R2)R3 [R1 = Ph, propan-2-yl, 4-chlorophenyl, etc.; R2 = H, Et, n-Pr, n-Bu, Bn, cyclohexyl; R3 = n-Bu, Bn, 2-(thiophen-2-yl)ethyl, etc.; R2R3 = -(CH2)5-, -(CH2)2O(CH2)2-] and I under mild conditions with broad substrate scope and good functional group tolerance. Most appealingly, the reaction can proceed smoothly without adding any strong oxidants. Control experiments and computational studies support a mechanism involving water-assisted in situ generation of thioureas and photocatalytic oxidative desulfurization. The present method provides a promising synthesis strategy for the formation of diverse and useful unsym. urea derivatives I in the fields of pharmaceutical and synthetic chem.
Green Chemistry published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 19241-24-8 belongs to class esters-buliding-blocks, and the molecular formula is C11H13NS, Computed Properties of 19241-24-8.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics