Recommanded Product: 4522-93-4On October 4, 2019 ,《Synthetic Methodologies for Perfluoroaryl-Substituted (Diaryl)methylphosphonates, -Phosphinates via SNAr Reaction》 was published in Journal of Organic Chemistry. The article was written by Fujii, Kohei; Ito, Shigekazu; Mikami, Koichi. The article contains the following contents:
The new synthetic methodologies for perfluoroaryl-substituted (diaryl)methylphosphonates, -phosphinates via nucleophilic aromatic substitution (SNAr) were developed. Benzylphosphonate and α-fluorobenzylphosphonate reacted with a wide variety of perfluoroarenes via SNAr reaction. The reaction took place quickly and gave perfluoroarylated phosphonates in high yields. Highly diastereoselective SNAr reaction with binaphthyl-based chiral phosphinates was further carried out. The experimental part of the paper was very detailed, including the reaction process of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Recommanded Product: 4522-93-4)
Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Recommanded Product: 4522-93-4 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics