HPLC of Formula: 623-47-2In 2019 ,《Design, efficient synthesis and antimicrobial evaluation of some novel pyrano[2,3-b][1,8]naphthyridine and pyrrolo [2,3-f][1,8] naphth-yridine derivatives》 was published in Pharma Chemica. The article was written by Elkanzi, Nadia Ali Ahmed; Ghoneim, Amira A.; Bakr, Rania B.. The article contains the following contents:
The synthesis of naphthyridine derivatives by the reaction of 4,11-diamino-1,6,6a,8,9,10-hexahydropyrano[2,3-b]pyrrolo[2,3-f][1,8]naphthyridine-3-carboxylic acid with aminobenzamidine dihydrochloride, benzotriazol-1yloxytris(pyrrolidino)phosphonium hexafluorophosphate and N-ethyldiisopropylamine afforded I and with Benzotriazol-1-yloxytris(pyrrolidino)phosphonium hexafluorophosphate, 4-cyanoaniline and N-ethyldiisopropylamine gave II with good and satisfied yield. The structures of synthesized compounds were established by IR, 1H-NMR, 13C-NMR and mass spectra. Antimicrobial activity of these compounds was evaluated against B. subtilis, S. aureus, E. coli, P. aeruginosa bacteria, A. flavus and C. albicans. The results revealed that the candidate III was found to be the most active against all the tested microorganisms. In the experiment, the researchers used many compounds, for example, Ethyl propiolate(cas: 623-47-2HPLC of Formula: 623-47-2)
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.HPLC of Formula: 623-47-2
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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics