Cai, Chen-Yan; Wu, Zheng-Jian; Liu, Ji-Ying; Chen, Ming; Song, Jinshuai; Xu, Hai-Chao published their research in Nature Communications in 2021. The article was titled 《Tailored cobalt-salen complexes enable electrocatalytic intramolecular allylic C-H functionalizations》.Category: esters-buliding-blocks The article contains the following contents:
Oxidative allylic C-H functionalization is a powerful tool to streamline organic synthesis as it minimizes the need for functional group activation and generates alkenyl-substituted products amenable to further chem. modifications. The intramol. variants can be used to construct functionalized ring structures but remain limited in scope and by their frequent requirement for noble metal catalysts and stoichiometric chem. oxidants. Here authors report an oxidant-free, electrocatalytic approach to achieve intramol. oxidative allylic C-H amination and alkylation by employing tailored cobalt-salen complexes as catalysts. These reactions proceed through a radical mechanism and display broad tolerance of functional groups and alkene substitution patterns, allowing efficient coupling of di-, tri- and even tetrasubstituted alkenes with N- and C-nucleophiles to furnish high-value heterocyclic and carbocyclic structures.Methyl 3-hydroxypropanoate(cas: 6149-41-3Category: esters-buliding-blocks) was used in this study.
Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics