The author of 《Computational, crystallographic studies, cytotoxicity and anti-tubercular activity of substituted 7-methoxy-indolizine analogues》 were Venugopala, Katharigatta Narayanaswamy; Chandrashekharappa, Sandeep; Pillay, Melendhran; Abdallah, Hassan H.; Mahomoodally, Fawzi M.; Bhandary, Subhrajyoti; Chopra, Deepak; Attimarad, Mahesh; Aldhubiab, Bandar E.; Nair, Anroop B.; Sreeharsha, Nagaraja; Morsy, Mohamed A.; Pottathil, Shinu; Venugopala, Rashmi; Odhav, Bharti; Mlisana, Koleka. And the article was published in PLoS One in 2019. Reference of Ethyl propiolate The author mentioned the following in the article:
A series of synthetic 7-methoxy-indolizine derivatives I [R1 = 4-F, 4-CN, 3-OMe, 4-Br; R2 = H, Me, CO2Et] were synthesized, characterized and evaluated for in vitro whole-cell anti-tuberculosis (TB) screening against susceptible (H37Rv) and multi-drug-resistant (MDR) strains of Mycobacterium tuberculosis (MTB) using the resazurin microplate assay method and cytotoxicity was evaluated using the MTT assay. The experimental process involved the reaction of Ethyl propiolate(cas: 623-47-2Reference of Ethyl propiolate)
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Reference of Ethyl propiolate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics