《Microwave induced synthesis, and pharmacological properties of novel 1-benzoyl-4-bromopyrrolo[1,2-a]quinoline-3-carboxylate analogues》 was published in Chemical Data Collections in 2020. These research results belong to Uppar, Vijayakumar; Mudnakudu-Nagaraju, Kiran K.; Basarikatti, Atiyaparveen I.; Chougala, Mallikarjun; Chandrashekharappa, Sandeep; Mohan, Mahendra K.; Banuprakash, Govindappa; Venugopala, Katharigatta N.; Ningegowda, Raghu; Padmashali, Basavaraj. Recommanded Product: Ethyl propiolate The article mentions the following:
Greener method of synthesis of benzo-fused indolizines like Et 4-Bromo-1-(substituted-benzoyl)pyrrolo[1,2-a]quinoline-3-carboxylate analoguos (I) [R1= H, 4-F, 4-CN; R2= Me, Et; R3= H, acetoxy] using the one-pot method with 3-bromo quinolone, phenacyl bromide and electron-deficient alkynes in the presence of triethylamine base with acetonitrile as a solvent. The structures of all the newly synthesized pyrrolo[1,2-a]quinoline I was confirmed by spectroscopic techniques. All the synthesized test compounds I were screened for their antibacterial activity using six different types of Gram-pos. and Gram-neg. bacterial strains. The compounds I [R1= 4-OMe; R2=R3= acetoxy], [R1= H; R2=R3= acetoxy] and [R1= H; R2= propanoyloxy; R3= H] exhibited a significant zone of inhibition against all six bacterial strains, and the test compound I [R1= 4-CN; R2=R3= acetoxy] showed potent free radical scavenging activity with the highest percentage inhibition of 49.27 at 100μg/mL. In the experimental materials used by the author, we found Ethyl propiolate(cas: 623-47-2Recommanded Product: Ethyl propiolate)
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Recommanded Product: Ethyl propiolate
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Ester – an overview | ScienceDirect Topics