In 2022,Savari, Mehdi; Varasteh-Moradi, Ali; Sayyed-Alangi, S. Zahra; Hossaini, Zinatossadat; Zafarmehrabian, Ramin published an article in Applied Organometallic Chemistry. The title of the article was 《Ag/Fe3O4/TiO2@MWCNTs as a reusable organometallic nanocatalyst promoted green synthesis of new pyridobenzoazepines: Study of biological activity and reduction of organic pollutants》.Quality Control of Ethyl propiolate The author mentioned the following in the article:
In this research, Ag/Fe3O4/TiO2@MWCNTs magnetic nanocomposites synthesized using water extract of Spinacia oleracea leaves, and the high performance of synthesized catalyst was confirmed by employing it in the multicomponent reaction of isatoic anhydride, N-methylimidazole, α-haloketones, electron-deficient acetylenic compounds, ammonium acetate, and Me epoxide in water at ambient temperature for the preparation of new pyridobenzoazepine derivatives such as I [X = H, Me, NO2, etc.; R1 = Me, Et; R2 = CO2Et, 4-MeC6H4, 4-MeOC6H4, etc.] in high yields. Also, the catalytic activity of the green synthesized Ag/Fe3O4/TiO2@MWCNTs was evaluated in the reduction of organic pollutants such as 4-nitrophenol in water at mild conditions. The results indicated that the biosynthesized magnetic nanocomposites (MNCs) have very high and effective catalytic activity for organic pollutants within few seconds. The synthesized compounds have OH group in their structure and for this reason might be showed good antioxidant activity. Also, employing Gram-pos. and Gram-neg. bacteria in the disk diffusion procedure confirmed antimicrobial effect of the some pyridobenzoazepine derivatives The results showed that synthesized compounds prevented the bacterial growth. This used procedure for preparation of pyridobenzoazepine derivatives have some advantages such as low reaction time, product with high yields, and simple separation of catalyst and products. The experimental process involved the reaction of Ethyl propiolate(cas: 623-47-2Quality Control of Ethyl propiolate)
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Quality Control of Ethyl propiolate
Referemce:
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