Miller, A. O.; Furin, G. G. published an article on February 28 ,1989. The article was titled 《Reaction of polyfluoro aromatic compounds with sodium nitrite》, and you may find the article in Zhurnal Organicheskoi Khimii.Category: esters-buliding-blocks The information in the text is summarized as follows:
Reaction of C6F5R (R = O2N, cyano, EtO2C) with NaNO2 in DMSO afforded p-RC6F4OH in 80, 90, and 80% yields, resp.; i.e., exclusively products of O substitution. C6HF5 afforded 2,3,5,6-tetrafluorophenol and 2,4,5-trifluoro-6-nitrophenol in a 3:1 ratio. O-substitution products are formed with electron-accepting R. In addition to this study using Ethyl 2,3,4,5,6-pentafluorobenzoate, there are many other studies that have used Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Category: esters-buliding-blocks) was used in this study.
Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics