《Induction of Apoptosis in Cancer Cells by Glutathione Transferase Inhibitor Mediated Hydrophobic Tagging Molecules》 was written by Li, Xiaona; Lu, Zirui; Wang, Cong; Li, Kebin; Xu, Fengrong; Xu, Ping; Niu, Yan. HPLC of Formula: 51857-17-1 And the article was included in ACS Medicinal Chemistry Letters in 2021. The article conveys some information:
The abnormally high expression of glutathione transferases is closely associated with cancer incidence and drug resistance. By introducing a hydrophobic moiety to the inhibitor structure, we organized a series of degraders of glutathione transferases and demonstrated them potently inducing apoptosis in cancer cells, presenting their pharmacol. potential in cancer therapy. The results came from multiple reactions, including the reaction of N-Boc-1,6-Diaminohexane(cas: 51857-17-1HPLC of Formula: 51857-17-1)
N-Boc-1,6-Diaminohexane(cas: 51857-17-1) can be used as a linear hexyl spacer (C6-spacer) to synthesize biodegradable poly(disulfide amine)s for gene delivery, a multifunctional dendrimer for theranostics and so on.HPLC of Formula: 51857-17-1
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