Li, Shuangshuang; Qiu, Ju; Li, Bowen; Sun, Zuolian; Xie, Peizhong; Loh, Teck-Peng published their research in Organic Chemistry Frontiers in 2021. The article was titled 《Practical allylation with unactivated allylic alcohols under mild conditions》.Category: esters-buliding-blocks The article contains the following contents:
A practical palladium/calcium catalytic system was developed for dehydrative allylation with unactivated allylic alcs. EtOH solvent with a H2O additive was identified as powerful medium to accelerate proton transfer. This catalytic system and environmentally benign medium enabled a variety of soft carbonic nucleophiles and allylic alcs. to react smoothly at room temperature with water as the only byproduct. A wide spectrum of allylic compounds bearing a variety of functional groups I [R = Me, CN, CO2Et, etc.; R1 = CO2Me, CO2Et; R2 = CN, NO2, CO2Me, CO2Et; R3 = H, Me; R4 = H, Me; R5 = Ph, 2-FC6H4, 2-thienyl, etc.] could be obtained with high to excellent yields. After reading the article, we found that the author used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Category: esters-buliding-blocks)
Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics