In 2006,Kim, Hoon Sik; Bae, Jin Yong; Lee, Je Seung; Jeong, Cheong Il; Choi, Dae Ki; Kang, Sang Ook; Cheong, Minserk published 《An efficient catalytic system for the carbomethoxylation of ethylene oxide》.Applied Catalysis, A: General published the findings.Synthetic Route of C4H8O3 The information in the text is summarized as follows:
Me β-hydroxypropionate (MHP), an intermediate to propane-1,3-diol (PDO) was produced in high yield from the carbomethoxylation of ethylene oxide (EO) using a catalytic system consisting of Co2(CO)8 and ZnX2L2 (1: L = pyridine; 2: L = phosphine; X = Cl, Br, I). The carbomethoxylation was greatly influenced by the variation of temperature and CO pressure. The increase of temperature increased the EO conversion, but decreased the selectivity to MHP. Both the yield and the selectivity of MHP increased with increasing CO pressure. FT-IR spectroscopic studies show that Co2(CO)8 interacts with (C5H5N)2ZnBr2, affording a new ionic cobalt carbonyl species. After reading the article, we found that the author used Methyl 3-hydroxypropanoate(cas: 6149-41-3Synthetic Route of C4H8O3)
Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Synthetic Route of C4H8O3
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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics