Dong, Jun; Du, Hongguang; Xu, Jiaxi published the artcile< Regiospecific synthesis of polysubstituted furans with mono- to tricarboxylates from various sulfonium acylmethylides and acetylenic esters>, COA of Formula: C11H12O3, the main research area is polysubstituted furan preparation regioselective; ylide alkyne tandem Michael addition nucleophilic ring opening elimination.
Polysubstituted furans I [R1 = CO2Me, CO2Et; R2 = H, CF3, CO2Me, CO2Et; R3 = H, CO2Me, CO2Et; R4 = Me, Ph, 1-naphthyl, etc.] were prepared in moderate to good yields from sulfur ylides and acetylenic esters. The direct reactions of dimethylsulfonium acylmethylides with acetylenic esters afforded furans I through a tandem sequence of Michael addition, intramol. nucleophilic addition, 4π ring opening, intramol. Michael addition and elimination. The method was extended to synthesize furan-3-carboxylate, -2,4-dicarboxylates, and -2,3,4-tricarboxylates as well. The current method provided a direct and simple strategy in synthesis of structurally diverse polysubstituted furans with mono- to tricarboxylate groups from safe and readily available dimethylsulfonium acylmethylides and different acetylenic esters.
RSC Advances published new progress about Elimination reaction. 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, COA of Formula: C11H12O3.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics