The author of 《Pyrrolecarboxylic acids. XXI. Theoretical and experimental aspects of the reactivities of carboxypyrroles.》 were Del Re, Giuseppe; Scarpati, Rachele. And the article was published in Rend. Accad. Sci. Fis. Mat. in 1964. Electric Literature of C8H9NO4 The author mentioned the following in the article:
cf. CA 62, 5173e. The results of a theor. and exptl. study on the 9 pyrrolecarboxylic acids are presented. The theor. part presents complete data on charges, energies, and localization energies for nucleophilic, radicalic, and electrophilic reactions of pyrrole and its carboxy derivatives The exptl. part, designed to provide a systematic test of the reactivities of the compounds in question involves the electrophilic formylation, hydrolysis, and mild oxidation of the various pyrrolecarboxylic acid Me esters. Paper-chromatog. of the resulting acids gives accurate data concerning the position of substitution in the products and a rough estimation of the relative yields. The exptl. data are used to discuss the theor. charge distribution and localization energies. Localization energies appear to give the best predictions, although some discrepancies still exist which are discussed extensively. In the experimental materials used by the author, we found Dimethyl 1H-pyrrole-2,3-dicarboxylate(cas: 2818-08-8Electric Literature of C8H9NO4)
Dimethyl 1H-pyrrole-2,3-dicarboxylate(cas: 2818-08-8) belongs to pyrroles. Pyrroles are components of more complex macrocycles, including the porphyrinogens and products derived therefrom, including porphyrins of heme, the chlorins, bacteriochlorins, and chlorophylls. Porphobilinogen, a trisubstituted pyrrole, is the biosynthetic precursor to many natural products such as heme.Electric Literature of C8H9NO4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics