Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoateOn November 30, 1981 ,《Fluoro ketones. V. Reactions of alkyl and aryllithium compounds with perfluoroalkyl ether esters》 appeared in Journal of Fluorine Chemistry. The author of the article were Chen, Loomis S.; Tamborski, Christ. The article conveys some information:
BuLi and aryllithium compounds reacted with a perfluoroalkyl ether ester at -78° to produce perfluoroalkyl ether ketones. Steric hindrance adjacent to the carbonyl group has an important effect on rates of reactions. Low reaction temperature is an important factor when secondary esters are used. At >-30° the decreased yields of ketone was due to the instability of the intermediate Li salt of the hemiketal which decomposed to an aryl ester and a perfluorinated olefin.Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoate) was used in this study.
Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters.Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoate They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics