In 2019,Journal of Organic Chemistry included an article by Biallas, Phillip; Mensak, Tobias M.; Kunz, Kevin-Alexander; Kirsch, Stefan F.. Quality Control of tert-Butyl (5-aminopentyl)carbamate. The article was titled 《The Deazidoalkoxylation: Sequential Nucleophilic Substitutions with Diazidated Diethyl Malonate》. The information in the text is summarized as follows:
Diazidated malonamides derived from amines and diazidated di-Et malonate react with lithiated alcs. through nucleophilic substitution reactions where azide acts as an unconventional leaving group. This deazidoalkoxylation leads to the formal construction of N,O-acetals, and the remaining azide functionality is a useful entry point for further functionalizations through, for example, standard cycloaddition chem. Thus, the presented chem. provides an easy route toward densely functionalized mols.: amines, alcs., and alkynes can be attached onto the small malonate core unit in a sequential manner. Safety: potentially hazardous geminal diazides should be handled with care. In the experiment, the researchers used tert-Butyl (5-aminopentyl)carbamate(cas: 51644-96-3Quality Control of tert-Butyl (5-aminopentyl)carbamate)
Some of the reported applications of tert-Butyl (5-aminopentyl)carbamate(cas: 51644-96-3) include: synthesis of of a supermacrocycle that self-assemble to form organic nanotubes., preparation of water-soluble unsymmetrical sulforhodamine fluorophores from monobrominated sulfoxanthene dye, synthesis of functionalized porphyrins as biocompatible carrier system for photodynamic therapy (PDT).Quality Control of tert-Butyl (5-aminopentyl)carbamate
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