Synthetic Route of C7H12O3In 2020 ,《Automated Synthesis of New Quinoxalinetacrines》 appeared in ChemistrySelect. The author of the article were Bautista-Aguilera, Oscar M.; Ismaili, Lhassane; Chioua, Mourad; Iriepa, Isabel; Angeles Martinez-Grau, Maria; Beadle, Christopher D.; Vetman, Tatiana; Lopez-Munoz, Francisco; Marco-Contelles, Jose. The article conveys some information:
The synthesis of novel quinoxalinetacrines e.g., I, a series of hybrids designed by juxtaposition of tacrine and quinoxaline is reported. The target compounds e.g., I have been obtained in moderate yields from 3-aminoquinoxaline-2-carbonitrile and suitable com. available ketones such as pentane-2,4-dione, 5,5-dimethylcyclohexane-1,3-dione, 1-benzoylpiperidin-4-one, etc. under microwave-promoted Friedlaender reactions catalyzed by aluminum trichloride or indium trichloride. These compounds e.g., I were synthesized remotely in Eli Lilly’s Automated Synthesis Laboratory as part of their Open Innovation Drug Discovery program. In addition to this study using Ethyl 3-oxopentanoate, there are many other studies that have used Ethyl 3-oxopentanoate(cas: 4949-44-4Synthetic Route of C7H12O3) was used in this study.
Ethyl 3-oxopentanoate(cas: 4949-44-4) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Synthetic Route of C7H12O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics