In 2009,Akritopoulou-Zanze, Irini; Wang, Ying; Zhao, Hongyu; Djuric, Stevan W. published 《Synthesis of substituted fused pyridines, pyrazines and pyrimidines by sequential Ugi/inverse electron demand Diels-Alder transformations》.Tetrahedron Letters published the findings.Electric Literature of C4H7NO2S The information in the text is summarized as follows:
The synthesis of all four regioisomers of fused pyrrolidino-pyridines in a 1-pot 2-step sequential Ugi-inverse-electron-demand Diels-Alder reaction is described. Fused pyrrolidinopyrazines, pyrrolidinopyrimidines, and azepinopyridines can also be obtained in consecutive synthetic sequences.Ethyl 2-amino-2-thioxoacetate(cas: 16982-21-1Electric Literature of C4H7NO2S) was used in this study.
Ethyl 2-amino-2-thioxoacetate(cas: 16982-21-1) belongs to anime. In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (NH3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines).Electric Literature of C4H7NO2S
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics