Su, Changlin; Li, Zhiyang; Zhang, Di; Wang, Zhimei; Zhou, Xin; Liao, Lifu; Xiao, Xilin published the artcile< A highly sensitive sensor based on a computer-designed magnetic molecularly imprinted membrane for the determination of acetaminophen>, Application of C18H26O6, the main research area is serum urine acetaminophen magnetic molecularly imprinted membrane; Acetaminophen; Carbon paste electrode; Electrochemical sensor; Magnetic molecularly imprinted membrane.
In this paper, a sensor based on a magnetic surface molecularly imprinted membrane (MMIP) was prepared for the highly sensitive and selective determination of acetaminophen (AP). Before the experiment, the appropriate functional monomers and solvents required for the polymer were screened, and the mol. electrostatic potentials (MEPs) were calculated by the DFT/B3LYP/6-31 + G method. MMIP with high recognition of AP was synthesized based on Fe3O4 coated SiO2nanoparticles (NPs) with excellent core-shell structure. Next, a carbon paste electrode (CPE) was filled with a piece of neodymium-iron-boron magnet to make magnetic electrode (MCPE), and MMIP/MCPE sensor was obtained by attaching a printed polymer to the surface of the electrode under the strong magnetic. Due to the stable mol. structure of the electrode surface, the sensor is highly effective and accurate for detection of AP using DPV. The DPV response of the sensor exhibited a linear dependence on the concentration of AP from 6 × 10-8 to 5 × 10-5 mol L-1 and 5 × 10-5 to 2 × 10-4 mol L-1, with a detection limit based on the lower linear range of 1.73 × 10-8 mol L-1(S/N = 3). When used for determination of AP in actual samples, the recovery of the sensor to the sample was 95.80-103.76%, and the RSD was 0.78%-3.05%.
Biosensors & Bioelectronics published new progress about Antibodies and Immunoglobulins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, Application of C18H26O6.
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