In 2019,Asian Journal of Organic Chemistry included an article by Ren, Zhi-Lin; Su, Lei; Cai, Shuang; Lu, Wen-Ting; Qiao, Yue; He, Ping; Ding, Ming-Wu. COA of Formula: C7H12O3. The article was titled 《Synthesis of Polysubstituted Pyridine Derivatives via Sequential AlCl3-Catalyzed Condensation/Aza-Wittig/Isomerization Reactions and A Study of Their Antifungal Activities》. The information in the text is summarized as follows:
A facile approach to access polysubstituted pyridine derivatives starting from Baylis-Hillman adducts was disclosed. The reactions proceeded smoothly by sequential AlCl3-catalyzed condensation/aza-Wittig/isomerization reactions leading to the target products at room temperature within 24 h in moderate to good yields. Furthermore, the final products were evaluated in mycelial growth tests against Pythium dissimile, Botryotinia fuckeliana and Zymoseptoria tritici and showed potential activities. In the experiment, the researchers used Ethyl 3-oxopentanoate(cas: 4949-44-4COA of Formula: C7H12O3)
Ethyl 3-oxopentanoate(cas: 4949-44-4) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.COA of Formula: C7H12O3
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