《Unprecedented Intramolecular Association-Induced Fluorescence in Tryptophan-Conjugated Peptidomimetics》 was written by Juneja, Shreya; Singh, Hanuman; Palui, Sayan; Trivedi, Shruti; Singh, Sharan S.; Haridas, V.; Pandey, Siddharth. Recommanded Product: tert-Butyl 7-benzyl-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate And the article was included in Journal of Physical Chemistry B on April 11 ,2019. The article conveys some information:
We report herewith tryptophan (Trp)-conjugated peptidomimetics that show intramol. through-space association between the Trp units. Our investigation revealed that the proximal placement of Trp can lead to the emergence of a new and unanticipated fluorescent entity constituting a Trp-Trp dimer. Proton-induced modulation of fluorescence is a consequence of this work. Investigations with control compounds unequivocally revealed that the fluorescence property is not originated from the localized excited state but from the unprecedented Trp-Trp intramol. dimer in the ground state itself. The present findings will initiate the biophys. scientists to have a relook at the fluorescence properties of Trp-containing proteins. After reading the article, we found that the author used tert-Butyl 7-benzyl-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate(cas: 227940-71-8Recommanded Product: tert-Butyl 7-benzyl-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate)
tert-Butyl 7-benzyl-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate(cas: 227940-71-8) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Recommanded Product: tert-Butyl 7-benzyl-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics