Zhang, Qi; Li, Yao; Zhang, Long; Luo, Sanzhong published their research in Angewandte Chemie, International Edition in 2021. The article was titled 《Catalytic Asymmetric Disulfuration by a Chiral Bulky Three-Component Lewis Acid-Base》.Application of 609-14-3 The article contains the following contents:
A three-component Lewis acid-base (Lewis trio) involving a bulky chiral primary amine, B(C6F5)3 and a bulky tertiary amine has been developed as an effective enamine catalyst for enantioselective disulfuration reactions. The bulky tertiary amine was found to activate a bulky primary-tertiary diamine-borane Lewis pair for enamine catalysis via frustrated interaction. The resulted chiral bulky Lewis trio (BLT) allows for the construction of chiral disulfides via direct disulfuration with β-ketocarbonyls or α-branched aldehydes in a practical and highly stereocontrolled manner. After reading the article, we found that the author used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Application of 609-14-3)
Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Application of 609-14-3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics