Recommanded Product: Methyl 4-fluoro-3-nitrobenzoateIn 2004 ,《Traceless Solid-Phase Synthesis of Substituted Benzimidazolones》 was published in Journal of Combinatorial Chemistry. The article was written by Wang, Chih-Chung; Li, Wen-Ren. The article contains the following contents:
A new approach to substituted benzimidazolones is described. The key step of the sequence involved the introduction of one of the nitrogens by nucleophilic addition of a carbamate to an o-fluoronitrobenzene. Spontaneous cyclization and detachment of the benzimidazolones from the resin occurred in high yields under reductive conditions on solid supports. To further expand the scale and incorporate a third element of diversity into the library of target mols., the benzimidazolones were treated with NaH and various alkyl halides in DMF to afford fully functionalized benzimidazolones. In the experimental materials used by the author, we found Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Recommanded Product: Methyl 4-fluoro-3-nitrobenzoate)
Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Recommanded Product: Methyl 4-fluoro-3-nitrobenzoate
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