In 2014,Tamiaki, Hitoshi; Isoda, Yasuaki; Tanaka, Takuya; Machida, Shinnosuke published 《Synthesis of chlorophyll-amino acid conjugates as models for modification of proteins with chromo/fluorophores》.Bioorganic & Medicinal Chemistry published the findings.Safety of Methyl 3-hydroxypropanoate The information in the text is summarized as follows:
A chlorophyll-a derivative bonded directly with epoxide at the peripheral position of the chlorin π-system was reacted with N-urethane and C-ester protected amino acids bearing an alc. or phenolic hydroxy group as well as a carboxy group at the residue to give chlorophyll-amino acid conjugates. The carboxy residues of N,C-protected aspartic and glutamic acids were esterified with the epoxide in high yields. The synthetic conjugates in dichloromethane had absorption bands throughout the visible region including intense red-side Qy and blue-side Soret bands. By their excitation at the visible bands, strong and efficient fluorescence emission was observed up to the near-IR region. The chromo/fluorophores are promising for preparation of functional peptides and modification of proteins. In the experimental materials used by the author, we found Methyl 3-hydroxypropanoate(cas: 6149-41-3Safety of Methyl 3-hydroxypropanoate)
Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Safety of Methyl 3-hydroxypropanoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics