《Design, Synthesis, and Anticancer Activity of 1,2,3-Triazole Linked Thiazole-1,2-isoxazole Derivatives》 was written by Yakantham, T.; Sreenivasulu, R.; Alluraiah, G.; Tej, M. B.; Ramesh Raju, R.. Name: Ethyl 2-amino-2-thioxoacetateThis research focused ontriazole thiazole isoxazole derivative preparation cancer. The article conveys some information:
Abstract: A series of novel 1,2,3-triazole linked thiazole-1,2-isoxazole derivatives has been designed, synthesized and characterized by 1H and 13C NMR, and mass spectral anal. The compounds have been tested for their anticancer activity towards MCF-7 (breast cancer), A549 (lung cancer), Colo-205 (colon cancer), and A2780 (ovarian cancer) by using the MTT method using etoposide as the reference Most of the tested compounds demonstrate good to moderate activity against all cell lines. The compounds 14b, 14e, 14g, and 14h are characterized by inhibitory activity stronger than that of etoposide. After reading the article, we found that the author used Ethyl 2-amino-2-thioxoacetate(cas: 16982-21-1Name: Ethyl 2-amino-2-thioxoacetate)
Ethyl 2-amino-2-thioxoacetate(cas: 16982-21-1) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.Name: Ethyl 2-amino-2-thioxoacetate
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