Saito, Masato; Kawamata, Yu; Meanwell, Michael; Navratil, Rafael; Chiodi, Debora; Carlson, Ethan; Hu, Pengfei; Chen, Longrui; Udyavara, Sagar; Kingston, Cian; Tanwar, Mayank; Tyagi, Sameer; McKillican, Bruce P.; Gichinga, Moses G.; Schmidt, Michael A.; Eastgate, Martin D.; Lamberto, Massimiliano; He, Chi; Tang, Tianhua; Malapit, Christian A.; Sigman, Matthew S.; Minteer, Shelley D.; Neurock, Matthew; Baran, Phil S. published an article in 2021. The article was titled 《N-Ammonium Ylide Mediators for Electrochemical C-H Oxidation》, and you may find the article in Journal of the American Chemical Society.Electric Literature of C4H5ClO3 The information in the text is summarized as follows:
Herein, a rationally designed platform that provides a step toward this challenge using N-ammonium ylides e.g., acetamidotrimethylazanium-tetrafluoroboranuide as electrochem. driven oxidants for site-specific, chemoselective C(sp3)-H oxidn was presented. By taking a first-principles approach guided by computation, these new mediators were identified and rapidly expanded into a library using ubiquitous building blocks and trivial synthesis techniques. The ylide-based approach to C-H oxidation exhibits tunable selectivity that is often exclusive to this class of oxidants and can be applied to real-world problems in the agricultural and pharmaceutical sectors. In addition to this study using Ethyl oxalyl monochloride, there are many other studies that have used Ethyl oxalyl monochloride(cas: 4755-77-5Electric Literature of C4H5ClO3) was used in this study.
Ethyl oxalyl monochloride(cas: 4755-77-5) belongs to acyl chlorides. Lacking the ability to form hydrogen bonds, acyl chlorides have lower boiling and melting points than similar carboxylic acids. For example, acetic acid boils at 118 °C, whereas acetyl chloride boils at 51 °C. Like most carbonyl compounds, infrared spectroscopy reveals a band near 1750 cm−1.Electric Literature of C4H5ClO3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics