Rammurthy, Banothu; Peraka, Swamy; Vasu, Amrutham; Krishna Sai, Gajula; Divya Rohini, Yennamaneni; Narender, Nama published their research in Asian Journal of Organic Chemistry in 2021. The article was titled 《Metal-free Catalytic Esterification of Aryl Alkyl Ketones with Alcohols via Free-radical Mediated C(sp3)-H Bond Oxygenation》.SDS of cas: 403-33-8 The article contains the following contents:
A novel metal-free catalytic one-pot approach has been developed for the esterification of aralkyl ketones RC(O)R1 (R = Ph, naphth-2-yl, 2-bromophenyl, etc.; R1 = Me, Et, benzyl) with alcs. R2OH (R2 = Me, Et, i-Pr, n-Bu) under open-air atm. conditions. The inexpensive iodide/oxone reagent system allowed the cascade C(sp3)-H bond oxygenation, selective C-C bond cleavage and esterification through the both radical and ionic pathways in a stepwise manner in one-pot. This mild, convenient and economically viable catalytic method tolerates the various functional groups to provide the corresponding alkyl benzoates RC(O)OR2 in up to 98% yields with up to 99% selectivity. The efficiency and feasibility of scale-up of the present catalytic system were demonstrated with gram scale experiments (up to 10 g scale).Methyl 4-fluorobenzoate(cas: 403-33-8SDS of cas: 403-33-8) was used in this study.
Methyl 4-fluorobenzoate(cas: 403-33-8) is an organic fluorinated building block used for the synthesis of various pharmaceutical compounds. It can be used for the preparation of Blonanserin.SDS of cas: 403-33-8
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics