Ma, Shichuang; Jiang, Weiqi; Li, Qi; Li, Tian; Wu, Wenjun; Bai, Hangyu; Shi, Baojun published an article in 2021. The article was titled 《Design, Synthesis, and Study of the Insecticidal Activity of Novel Steroidal 1,3,4-Oxadiazoles》, and you may find the article in Journal of Agricultural and Food Chemistry.Quality Control of Ethyl oxalyl monochloride The information in the text is summarized as follows:
A series of novel steroidal derivatives with a substituted 1,3,4-oxadiazole structure was designed and synthesized, and the target compounds were evaluated for their insecticidal activity against five aphid species. Most of the tested compounds exhibited potent insecticidal activity against Eriosoma lanigerum (Hausmann), Myzus persicae, and Aphis citricola. Compounds (I) and (II) displayed the highest activity against E. lanigerum, showing LC50 values of 27.6 and 30.4 μg/mL, resp. Ultrastructural changes in the midgut cells of E. lanigerum were detected by transmission electron microscopy, indicating that these steroidal oxazole derivatives might exert their insecticidal activity by destroying the mitochondria and nuclear membranes in insect midgut cells. Furthermore, a field trial showed that compound I exhibited effects similar to those of the pos. controls chlorpyrifos and thiamethoxam against E. lanigerum, reaching a control rate of 89.5% at a dose of 200 μg/mL after 21 days. We also investigated the hydrolysis and metabolism of the target compounds in E. lanigerum by assaying the activities of three insecticide-detoxifying enzymes. Compound I at 50 μg/mL exhibited inhibitory action on carboxylesterase similar to the known inhibitor tri-Ph phosphate. The above results demonstrate the potential of these steroidal oxazole derivatives to be developed as novel pesticides. In the experiment, the researchers used Ethyl oxalyl monochloride(cas: 4755-77-5Quality Control of Ethyl oxalyl monochloride)
Ethyl oxalyl monochloride(cas: 4755-77-5) belongs to acyl chlorides. Lacking the ability to form hydrogen bonds, acyl chlorides have lower boiling and melting points than similar carboxylic acids. For example, acetic acid boils at 118 °C, whereas acetyl chloride boils at 51 °C. Like most carbonyl compounds, infrared spectroscopy reveals a band near 1750 cm−1.Quality Control of Ethyl oxalyl monochloride
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics