Kleinbeck, Florian; Toste, F. Dean published the artcile< Gold(I)-Catalyzed Enantioselective Ring Expansion of Allenylcyclopropanols>, Synthetic Route of 112-63-0, the main research area is allenylcyclopropanol preparation chiral gold catalyst preparation ring expansion; cyclobutanone vinyl derivative stereoselective preparation crystal structure.
The asym. gold(I)-catalyzed ring expansion of 1-allenylcyclopropanols is described. The method provides synthetically valuable cyclobutanones with a vinyl-substituted quaternary stereogenic center in high enantioselectivities and yields. The method shows a broad substrate scope, tolerating protected alcs. and amines, alkenes, unsaturated esters, and acetals. The reaction is easily adjustable to large-scale synthesis, leading to product formation without significant loss of selectivity or yield with only 0.5 mol% catalyst loading.
Journal of the American Chemical Society published new progress about Alcohols, propargyl Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics