Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoateOn September 28, 2016 ,《Asymmetric Catalysis with Organic Azides and Diazo Compounds Initiated by Photoinduced Electron Transfer》 was published in Journal of the American Chemical Society. The article was written by Huang, Xiaoqiang; Webster, Richard D.; Harms, Klaus; Meggers, Eric. The article contains the following contents:
Electron-acceptor-substituted aryl azides and α-diazo carboxylic esters are used as substrates for visible-light-activated asym. α-amination and α-alkylation, resp., of 2-acyl imidazoles catalyzed by a chiral-at-metal rhodium-based Lewis acid in combination with a photoredox sensitizer. This novel proton- and redox-neutral method provides yields of up to 99% and excellent enantioselectivities of up to >99% ee with broad functional group compatibility. Mechanistic investigations suggest that an intermediate rhodium enolate complex acts as a reductive quencher to initiate a radical process with the aryl azides and α-diazo carboxylic esters serving as precursors for nitrogen and carbon-centered radicals, resp. This is the first report on using aryl azides and α-diazo carboxylic esters as substrates for asym. catalysis under photoredox conditions. These reagents have the advantage that mol. nitrogen is the leaving group and sole byproduct in this reaction. In the experimental materials used by the author, we found Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoate)
Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics