Application In Synthesis of Methyl 4′-formyl-[1,1′-biphenyl]-2-carboxylateOn May 13, 2015 ,《Simple Amine-Directed Meta-Selective C-H Arylation via Pd/Norbornene Catalysis》 appeared in Journal of the American Chemical Society. The author of the article were Dong, Zhe; Wang, Jianchun; Dong, Guangbin. The article conveys some information:
Herein we report a highly meta-selective C-H arylation using simple tertiary amines as the directing group. This method takes advantage of Pd/norbornene catalysis, offering a distinct strategy to control the site selectivity. The reaction was promoted by com. available AsPh3 as the ligand and a unique “”acetate cocktail””. Aryl iodides with an ortho electron-withdrawing group were employed as the coupling partner. A wide range of functional groups, including some heteroarenes, are tolerated under the reaction conditions. In addition, the amine directing group can be easily installed and transformed to other common versatile functional groups. We expect this C-H functionalization mode to have broad implications for developing other meta-selective transformations beyond this work. In the experiment, the researchers used many compounds, for example, Methyl 4′-formyl-[1,1′-biphenyl]-2-carboxylate(cas: 144291-47-4Application In Synthesis of Methyl 4′-formyl-[1,1′-biphenyl]-2-carboxylate)
Methyl 4′-formyl-[1,1′-biphenyl]-2-carboxylate(cas: 144291-47-4) belongs to esters.Application In Synthesis of Methyl 4′-formyl-[1,1′-biphenyl]-2-carboxylate They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.
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Ester – an overview | ScienceDirect Topics