In 2014,Chemistry – A European Journal included an article by Cairns, Andrew G.; Senn, Hans Martin; Murphy, Michael P.; Hartley, Richard C.. Product Details of 1073353-89-5. The article was titled 《Expanding the Palette of Phenanthridinium Cations》. The information in the text is summarized as follows:
5,6-Disubstituted phenanthridinium cations have a range of redox, fluorescence and biol. properties. Some properties rely on phenanthridiniums intercalating into DNA, but the use of these cations as exomarkers for the reactive oxygen species (ROS), superoxide, and as inhibitors of acetylcholine esterase (AChE) do not require intercalation. A versatile modular synthesis of 5,6-disubstituted phenanthridiniums that introduces diversity by Suzuki-Miyaura coupling, imine formation and microwave-assisted cyclization is presented. Computational modeling at the d. functional theory (DFT) level reveals that the novel displacement of the aryl halide by an acyclic N-alkylimine proceeds by an SNAr mechanism rather than electrocyclization. It is found that the displacement of halide is concerted and there is no stable Meisenheimer intermediate, provided the calculations consistently use a polarizable solvent model and a diffuse basis set. After reading the article, we found that the author used 2-(2-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 1073353-89-5Product Details of 1073353-89-5)
2-(2-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 1073353-89-5) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Product Details of 1073353-89-5 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics