Wenkert, Ernest; Sprague, P. W.; Webb, R. L. published the artcile< General methods of synthesis of indole alkaloids. XII. Synthesis of dl-18,19-dihydroantirhine and methyl demethylilludinate>, Recommanded Product: Methyl 4-methylnicotinate, the main research area is indole alkaloid; illudinininate demethyl; antirhine dihydro; pyridine alkaloid; demethylilludinininate methyl; dihydroantirhine.
Methyl nicotinate I (R = R1 = H) was condensed with MeCHO to give I (RR1 = MeCH:) and with 3,3-dimethylcyclopentanone to give I, (RR1 = 3,3-dimethylcyclopentylidene). Reduction, and oxidation of the I (RR1 = MeCH:) led to lactone II and thence in 3 steps to an antirhine derivative (±)III. Esterification and cyclization of I (RR1 = 3,3-dimethylcyclopentylidene) afforded an illudinine derivative IV.
Journal of Organic Chemistry published new progress about Alkaloids. 33402-75-4 belongs to class esters-buliding-blocks, and the molecular formula is C8H9NO2, Recommanded Product: Methyl 4-methylnicotinate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics