Otevrel, Jan; Svestka, David; Bobal, Pavel published the artcile< Bianthryl-based organocatalysts for the asymmetric Henry reaction of fluoroketones>, COA of Formula: C19H34O2, the main research area is alc preparation enantioselective; fluoroketone nitroalkane Henry reaction bianthryl catalyst; bianthryl organocatalyst preparation.
A catalytic system based on bianthrylbis(thiourea), e.g., I for the asym. Henry reaction of fluoroketones R1C(O)C(F2)R2 (R1 = Ph, thiophen-2-yl, 3-nitrophenyl, etc.; R2 = H, F) and nitroalkanes R3CH2NO2 (R3 = H, Me) that resulted from the screening of a library containing 31 chiral non-racemic organocatalysts has been developed. The corresponding adducts R1C(OH)(C(F2)R2)CH(NO2)R3 were isolated in up to 6 times shorter reaction time in comparison with the previously published organocatalysts. High levels of stereocontrol have been generally observed, with measured product enantiomeric excesses up to 97% and diastereomeric ratio 3 : 2 (anti/syn). The above-mentioned catalysts have been successfully applied to the total asym. synthesis of CF3-tethered (S)-halostachine, which has proved that this method constitutes an easy entry to similar enantiopure compounds
Organic & Biomolecular Chemistry published new progress about Enantioselective synthesis. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics