Moser, Russell J.; Brown, Ellis V. published the artcile< Decarboxylation of 5-substituted 2-pyridinecarboxylic acids>, Category: esters-buliding-blocks, the main research area is thermodn pyridinecarboxylate decarboxylation.
The rates of decarboxylation of 5-nitro-2-pyridinecarboxylic, 2,5-pyridinedicarboxylic, 5-iodo-2-pyridinecarboxylic, and 5-methoxy-2-pyridinecarboxylic acids in 3-nitrotoluene were measured. The ΔG, ΔH, and dS were calculated An examination of the linear free energy plot of relative rates vs. the σp constants, suggests that electron withdrawal from the 5-position results in lower ΔG values. The observation that 2-pyridinecarboxylic acid (I) does not fall on the same straight line as these acids suggests that I can either lead to a cyclic transition state or to a zwitterion intermediate which then decarboxylates. The pathway that a particularly substituted 2-pyridinecarboxylic acid follows depends upon the electron density on the ring N. A mechanism is given which is consistent with the available data. An assumption of this interpretation is that some monomer exists in solution at high temperature
Journal of Organic Chemistry published new progress about Decarboxylation kinetics. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics